Mission to Amish People was founded in 2001 with the purpose of evangelizing and discipling Amish and Former Amish as well as assisting those that leave the Amish by providing education, housing, and basic life skill training. read more...

Genetic Mutation in Amish Linked to Longer Life

November 16, 2017

A genetic mutation in an Amish community in Indiana that can cause fatal blood clotting has been linked to longevity and protection against diabetes, according to a study published in Science Advances this week (November 15).

Previous research has shown that the gene in question, SERPINE1, produces a protein that can promote aging in mice. Levels of the protein, called plasminogen activator inhibitor type 1 (PAI-1), are higher in patients with diabetes, obesity, or cardiovascular disease. PAI-1 is also known to play an important role in blood clotting, and people with two defect copies of SERPINE1 suffer from blood clotting disorders, Science reported.

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